GrippeCanadaV3, Main, Exploration, bibRecord, 000072

Virological Surveillance of Influenza A Subtypes Isolated in 2014 from Clinical Outbreaks in Canadian Swine.

Identifieur interne : 000072 ( Main/Exploration ); précédent : 000071; suivant : 000073

Virological Surveillance of Influenza A Subtypes Isolated in 2014 from Clinical Outbreaks in Canadian Swine.

Auteurs : Helena Grgi [Canada] ; Jackie Gallant [Canada] ; Zvonimir Poljak [Canada]

Source :

Viruses [ 1999-4915 ] ; 2017.

RBID : pubmed:28335552

Descripteurs français

KwdFr :
- Analyse de regroupements, Animaux, Canada (épidémiologie), Flambées de maladies, Infections à Orthomyxoviridae (médecine vétérinaire), Infections à Orthomyxoviridae (virologie), Infections à Orthomyxoviridae (épidémiologie), Maladies des porcs (virologie), Maladies des porcs (épidémiologie), Phylogénie, Suidae, Variation des antigènes, Variation génétique, Virus de la grippe A (), Virus de la grippe A (génétique), Virus de la grippe A (isolement et purification), Épidémiologie moléculaire, Épidémiosurveillance.
MESH :
- génétique : Virus de la grippe A.
- isolement et purification : Virus de la grippe A.
- médecine vétérinaire : Infections à Orthomyxoviridae.
- virologie : Infections à Orthomyxoviridae, Maladies des porcs.
- épidémiologie : Canada, Infections à Orthomyxoviridae, Maladies des porcs.
- Analyse de regroupements, Animaux, Flambées de maladies, Phylogénie, Suidae, Variation des antigènes, Variation génétique, Virus de la grippe A, Épidémiologie moléculaire, Épidémiosurveillance.

English descriptors

KwdEn :
- Animals, Antigenic Variation, Canada (epidemiology), Cluster Analysis, Disease Outbreaks, Epidemiological Monitoring, Genetic Variation, Influenza A virus (classification), Influenza A virus (genetics), Influenza A virus (isolation & purification), Molecular Epidemiology, Orthomyxoviridae Infections (epidemiology), Orthomyxoviridae Infections (veterinary), Orthomyxoviridae Infections (virology), Phylogeny, Swine, Swine Diseases (epidemiology), Swine Diseases (virology).
MESH :
- classification : Influenza A virus.
- epidemiology : Canada, Orthomyxoviridae Infections, Swine Diseases.
- genetics : Influenza A virus.
- isolation & purification : Influenza A virus.
- veterinary : Orthomyxoviridae Infections.
- virology : Orthomyxoviridae Infections, Swine Diseases.
- Animals, Antigenic Variation, Cluster Analysis, Disease Outbreaks, Epidemiological Monitoring, Genetic Variation, Molecular Epidemiology, Phylogeny, Swine.

Abstract

Influenza A viruses (IAVs) are respiratory pathogens associated with an acute respiratory disease that occurs year-round in swine production. It is currently one of the most important pathogens in swine populations, with the potential to infect other host species including humans. Ongoing research indicates that the three major subtypes of IAV-H1N1, H1N2, and H3N2-continue to expand in their genetic and antigenic diversity. In this study, we conducted a comprehensive genomic analysis of 16 IAVs isolated from different clinical outbreaks in Alberta, Manitoba, Ontario, and Saskatchewan in 2014. We also examined the genetic basis for probable antigenic differences among sequenced viruses. On the basis of phylogenetic analysis, all 13 Canadian H3N2 viruses belonged to cluster IV, eight H3N2 viruses were part of the IV-C cluster, and one virus belonged to the IV-B and one to the IV-D cluster. Based on standards used in this study, three H3N2 viruses could not be clearly classified into any currently established group within cluster IV (A to F). Three H1N2 viruses were part of the H1α cluster.

DOI: 10.3390/v9030055
PubMed: 28335552

Affiliations:

Canada

Links toward previous steps (curation, corpus...)

to stream Main, to step Corpus: 000096
to stream Main, to step Curation: 000096

Le document en format XML

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<front><div type="abstract" xml:lang="en">Influenza A viruses (IAVs) are respiratory pathogens associated with an acute respiratory disease that occurs year-round in swine production. It is currently one of the most important pathogens in swine populations, with the potential to infect other host species including humans. Ongoing research indicates that the three major subtypes of IAV-H1N1, H1N2, and H3N2-continue to expand in their genetic and antigenic diversity. In this study, we conducted a comprehensive genomic analysis of 16 IAVs isolated from different clinical outbreaks in Alberta, Manitoba, Ontario, and Saskatchewan in 2014. We also examined the genetic basis for probable antigenic differences among sequenced viruses. On the basis of phylogenetic analysis, all 13 Canadian H3N2 viruses belonged to cluster IV, eight H3N2 viruses were part of the IV-C cluster, and one virus belonged to the IV-B and one to the IV-D cluster. Based on standards used in this study, three H3N2 viruses could not be clearly classified into any currently established group within cluster IV (A to F). Three H1N2 viruses were part of the H1α cluster.</div>
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Virological Surveillance of Influenza A Subtypes Isolated in 2014 from Clinical Outbreaks in Canadian Swine.

Virological Surveillance of Influenza A Subtypes Isolated in 2014 from Clinical Outbreaks in Canadian Swine.

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